Preparation of patients for BM/HSC
BM/HSC transplantations require the prior conditioning (preparation) of patients for transplantation. Conditioning of a patient for a BM/HSC transplant is a critical element of the procedure, serving two main purposes:
- It provides adequate immunosuppression of the patient and clears sufficient niche space in the bone marrow for the transplanted HSC. This allows transplanted cells to engraft in the recipient.
- It often helps to eradicate the source of the malignancy